Essential, primary or idiopathic hypertension is defined as high BP in which secondary causes such as renovascular disease, renal failure, pheochromocytoma, aldosteronism, or other causes of secondary hypertension or mendelian forms monogenic are not present.
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A number of factors are known to increase BP, including 1 obesity, 2 insulin resistance, 3 high alcohol intake, 4 high salt intake in salt—sensitive patients , 5 aging 6 sedentary lifestyle, 7 stress, 8 low potassium intake, and 9 low calcium intake Sever, Thus, identification of the gene responsible may help clarify some of the genetic alterations in this form of essential hypertension.
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- USA The mechanism by which alcohol raises BP is not known. We also would like to thank Dr Abdulwahid Aldehaimi the head of the Pathology and Clinical laboratory at KFMC for his kind support and encouragement and also our thanks extend to members of staff of immunology and serology laboratory for their specific technical support. This is the second orphan drug designation for tesevatinib; the first designation was granted in March for the treatment of autosomal recessive polycystic kidney disease ARPKD.
There is a strong positive and continuous correlation between BP and the risk of cardiovascular disease CVD , renal disease, and mortality. Diagnostic considerations with inherited platelet disorder testing: A hypothesis for the pathogenesis of essential hypertension: It is worth noting that some alleles such asVic Man: So spot on :)
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